Boe made her acting debut in 2008, when she landed a role of Child Lisa in a horror film, Amusement. A year later she appeared in the film, He's On My Mind, as Laci and in 2012 in Paranormal Activity 4 as Tara. In 2014, she guest-starred in two shows, in January as Tracy McCoy, Cameron Tucker's student in Modern Family, and in July, as Brynn Hendry in two episodes of the thriller show Extant. In November 2014, she joined the cast of NBC's soap opera drama series Days of Our Lives in a recurring role of Daphne. She debuted on November 14, 2014. In 2017 she played the role Jessica in the Netflix series 13 Reasons Why.